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MINISTRY OF EDUCATION AND TRAINING MINISTRY OF HEALTH HANOI MEDICAL UNIVERSITY LY MINH ĐUC EVALUATION OF VISION FUNCTION OF STUDENTS IN POLICE ACADEMIES AND UNIVERSITIES IN HANOI Specialization: Ophthalmology Code: 62720157 DOCTORAL THESIS SUMMARY HA NOI – 2020 The work was completed at: HANOI MEDICAL UNIVERSITY Science instructor: 1. Associate Professor, Ph.D Le Thi Kim Xuan 2. Associate Professor, Ph.D Nguyen Đuc Anh Reviewer 1: Reviewer 2: Reviewer 3: The thesis has been defended in front of the State-level Council of Thesis Grading Meeting at: Hanoi Medical University At , , , 2020. The thesis can be found at: - National Library - Hanoi Medical University's Library WORKS RELATED TO THE THESIS PUBLISHED 1. Ly Minh Đuc, Le Thi Kim Xuan (2019). Current situation of short-sightedness of students of Public Security Academies and Universities in Hanoi in the academic year 2016-2017. Journal of Practical Medicine. 6 (1101). 103-107. 2. Ly Minh Đuc, Le Thi Kim Xuan (2019). Current situation of the regulation ability of students of Public Security Academies and Universities in Hanoi in the academic year 2017-2018. Journal of Practical Medicine. 6 (1101). 122-126. 3. Ly Minh Đuc, Le Thi Kim Xuan (2019). Survey of color vision in students of some Hanoi Public Security schools with Ishihara board. Journal of Practical Medicine. 12 (1123). 5256. 4. Ly Minh Đuc, Le Thi Kim Xuan (2020). Survey of stereoscopic vision in 3rd year students of Public Security Academies and Universities in Hanoi. Vietnam Journal of Medicine.1 (No. 486). 70-74. 1 INTRODUCTION Vision is one of the five important senses of humans. The current gold standard in assessing visual function is vision, but sometimes vision is an indicator that provides only a limited amount of information obtained in the current living condition. The patient's vision is not merely based on the results of the optometry but also in combination with other examinations such as stereoscopic vision, color vision and contrast vision. Studies of visual function in the world show that, in Asia, myopia is an important health problem in the student community, myopia rate is often high in countries: China, Japan, Taiwan and Singapore, in which Taiwan's rate of myopia in students age 18 is 80%. Magosha Knutelska (2003) states that stereoscopic vision is best achieved before age 30 and the worst after 60 years. The rate of congenital color disorder according to the study of Mohd Fareed (2015) in men is 7.52% and in women is 0.83%. In Vietnam, there are a number of researches to screen for congenital color disorders and refractive errors, a study by Nguyen Thi Mai Dung (2006) shows that the rate of male color disorders is 3.01%, in women it is 1.35%. Phi Vinh Bao's study (2017) found that the rate of myopia in military students was 16.9%. For the police, due to the professional characteristics, the detection of visual dysfunction is very important in practical work. In particular, students of police schools play a key role in the fight to preserve order and protect the National security. Comprehensive study of visual function will provide sufficient information, help us to plan and implement policies to enhance the visual function of police students in particular and for the police force in general. Recognizing the importance and impact of the above issues, we conducted research on the subject: "Assessment of visual function in students of Hanoi Regional Police Universities and Public Security Institutes" with the following aims: 1. Describe the situation of visual function in 3rd year students at 4 Hanoi Academy and Public Security Schools in 2017. 2. Identify factors affecting visual function in 2017. 3. Assess the effectiveness of interventional health education communication interventions for nearsighted progress in 20172018. 2 THESIS’S NOVEL CONTRIBUTION - This is the first descriptive and interventional study in Vietnam to evaluate comprehensively the visual function, allowing the evaluation of factors affecting visual function, thereby appropriately applying various methods of changing behavior to improve visual quality. - This is the first time research subjects are Police students. The entrance examination for police schools is very tight, but only stops at vision and refractive exams. Therefore, a comprehensive assessment of visual function requires other examinations such as: Stereoscopic vision, color vision, and contrast vision, have shown us that there are cases of good vision that still experience visual dysfunction. STRUCTURE OF THE THESIS The thesis consists of 128 pages, including the Introduction (2 pages) and 4 chapters Chapter 1: Overview (38 pages), Chapter 2: Subjects and research methods (19 pages), Chapter 3: Research results (31 pages), Chapter 4: Discussion (34 pages), Conclusion (2 pages), new contributions (1 page), Recommendations (1 page). There are also: section of references, appendices, tables, charts, illustrations of the results. CHAPTER 1: OVERVIEW 1.1. SOME CONCEPTS AND METHODS OF MEASURING VISUAL FUNCTION 1.1.1. Visual acuity 1.1.1.1. Definition Visual acuity is an important part of the visual function, it consists of many components, mainly the ability to distinguish light and the ability to distinguish space. Visual acuity examination is a fundamental and important part of ophthalmology. Visual acuity assessment should always include both distant vision and near vision. Normally, the distant vision and near vision are always equal. Certain conditions affecting the eye's regulation, such as presbyopia, unattended farsightedness, or cataract, etc., can cause near vision loss, while distant vision is not affected. Vision examinations will give us information about: - Eye refractive condition. - Macular function. - The integrity of the optic nerve conduction pathway. - It is possible to compare the sight of one eye to two eyes or between two eyes to know the vision of the eyes. 3 1.1.1.2. The examination of visual acuity There are many visual function tests used to measure an aspect of the ability to see clearly or identify target details of the visual system. These exams include: Minimum detectable resolution The detection threshold is the threshold of a person's visual system that detects the presence of a point or line on its background. Minimum resolution The threshold of recognition is the ability to resolve details. Clinical vision measurement is based on this type of visual function. Minimum separable or vernier acuity Vernier acuity is the ability of a person to detect whether a group of points or lines is separate and distinct or not. 1.1.2. Stereoscopic vision 1.1.2.1. Definition Stereoscopic vision is the ability to perceive two images that are nearly identical from the two-eye retina uniting to form a complete image with full details in all three dimensions. Stereo eyesight is considered to be the highest level of binocular vision. Stereo stereometry is one of the most important examinations when we conduct vision assessment on children, because it brings a lot of information about the development of the child's visual system. 1.1.2.2. Classification of stereoscopic vision - High-quality stereoscopic vision, also known as fine stereoscopic vision Response to high spatial frequencies (sophisticated details). - Rough stereoscopic vision mainly responds to low-frequency spatial targets (large objects). 1.1.2.3. Methods to measure stereoscopic vision Stereoscopic vision is possible due to the difference in binocular images. This difference can be created in two ways: - Through the stereoscopic images: where two 3-dimensional images are seen in each eye separately, but the correct 3-dimensional image is obtained when there is a visual difference between the right eye and the left eye. For example, Fly test board, animals and Wirt rings of Randot board. - Through random dot stereographic images in which 3-dimensional images are not visible with separate right or left eye, only see when there is information difference between right eye and left eye. For example: Lang table, Randot picture board. Some stereoscopic vision tables commonly are used in clinical practice: 4 Fly test table and Random Dot test table 1.1.3. Color vision 1.1.3.1. Definition Color vision is a visual function that allows one to be aware of the different wavelengths of light of the visible spectrum, the ability of the eye to discern the colors produced by the interaction of billions of cells. nerve on the cerebral cortex. 1.1.3.2. Color vision disorders Color vision disorders are one of the most common visual disorderss, characterized by reduced or inability to distinguish colors one of the main functions of vision. Color vision disorders may be due to congenital or acquired disorderss. Congenital color vision disorders Congenital color vision disorders are genetic damage related to gender. It is found that about 7-8% of men and about 0.4% of women have such a disorders. Today, congenital color vision disorders has been shown to be a genetic disease in genes. Color blindness on the red-green scale is the recessive inherited disease on the sex chromosome, and the color blindness on the blue-yellow scale is dominant on the normal chromosome. Color blindness is divided into 3 categories: (1) Total color blindness: People who have total color blindness do not have two or three types of cones. (2) One-color blindness One-color blind people are completely or partially missing the cone cell pigment system. - Red blindness: is an abnormality of red light absorbing pigment. - Green blindness: is an abnormality of green light absorbing pigment. - Blue blindness: is an abnormality of blue light absorbing pigment. 5 (3) Color vision disorders: People who have color vision disorders have a completely or partially altered cone cell pigment system Color vision disorders are divided into: - Red weak blindness: almost similar to red blind, perceive red darker than normal. - Green weak blindness: almost similar to green blind, perceive green darker than normal. - Blue weak blindness: Difficult to distinguish green and blue, very rare and often acquired, or accompanied by red - green disorderss. Acquired color vision disorders Acquired color vision disorders is the lack of color perception caused by eye diseases. Acquired color vision disorders are more common than congenital color vision disorder. The incidence rates are similar for both sexes, with an estimated 5% of the population. Chronic conditions that can lead to color blindness include Alzheimer's disease, diabetes, glaucoma, etc., accidents or strokes, medications such as antibiotics, barbiturates, anti-tuberculosis drugs, and high medications. Blood pressure and some medications to treat neurological disorders can also cause color blindness. 1.1.3.3. Examination method for Color vision disorders The method of using the Ishihara color palette is the most widely used, it is considered the most effective examination to screen for congenital color disorders on the red-green scale. Ishihara color vision board 1.1.4. Contrast vision 1.1.4.1. Definition of Contrast Contrast is created by the difference in brightness, the amount of light reflected from two adjacent surfaces. Contrast has a particularly important meaning for sight. It is a physiological function of the visual 6 function that can alter and greatly affect the ability to distinguish stimuli during visual perception. 1.1.4.3. Contrast vision Contrast vision is produced on the basis of differences in brightness. Strongly lit areas of the retina have a positive effect on areas with weaker lighting, or the opposite of weakly lit areas can be reversed. Examination methods of contrast vision There are two methods of contrast vision measurement currently in use: measuring gratings and letter contrast vision Clinically often use letter contrast vision method. Bailey-Lovie and Pelli-Robson vision chart The role of contrast vision Contrast vision measurement allows us to determine the least amount of contrast needed to detect a visual stimulus and gives us a more complete result of the patient's visual function. 1.2. RESEARCH SITUATION ON STEREOSCOPIC VISION, COLOR VISION AND CONTRAST VISION 1.2.1. Worldwide 1.2.1.1. Research on stereoscopic vision G. Research Heron et al. (1985) demonstrated that stereoscopic vision tends to improve and develop with age. Research by Magosha K et al. (2003) suggested that stereoscopic vision is best achieved before age 30 and least after 60 years. 1.2.1.2. Research on color vision Research by Karim J Karim et al. (2013) showed that 8.47% of male students, 1.37% of female students were found to have congenital color disorder in the student population, university students of Erbil city in Kurdistan-Iraq region 7 1.2.1.3. Research on contrast vision A study by Yamane N et al. (2004) found that contrast vision decreased significantly in Lasik surgical subjects with myopia treatment. 1.2.2. In Vietnam Research on visual function in Vietnam has not been deeply concerned and evaluated comprehensively, there are a number of researches to screen for congenital color disorders using Ishihara test. A study by Tran Thi Thanh et al (2012) on the first-year students of Hai Phong Medical University showed that the prevalence of color vision disorder in men is 8.05% and there is no case of color vision disorder in women. Currently, there is no research on stereoscopic vision and contrast vision in Vietnam Therefore, a comprehensive study of visual function is a practical and very new issue in Vietnam. CHAPTER 2 SUBJECTS AND METHODS OF THE STUDY 2.1. SUBJECTS OF THE STUDY • Subjects selected for the study: third year students at the Hanoi regional Police Academies and Universities • Selection criteria: Participants in the study were in good health, no systemic diseases, no history of eye injury, traumatic brain injury. • Exclusion criteria: students with physical damage to their eyes. 2.2. METHODS OF THE STUDY 2.2.1. Research design - Cross-sectional descriptive study: to determine the visual disorder rate of police students. - Intervention research: to assess the effect of behavioral changes on myopia progression. 2.2.2. Study sample size 2.2.2.1. Cross-sectional descriptive study Sample size Apply the formula of an estimated 1-ratio sample size in population. n = Z (1− / 2) 2 p(1 − p) e2 Therein: n: number of researched students Z1-α/2: confidence limit, with a 95% confidence → Z1- α 2 = 1,96 p: The rate of visual disorder in students is estimated according to the previous research results, which is 10.14%. e: expected deviation e = 0.03 8 Plug the number into the formula we have: n = 389, practical study of 400 students. 2.2.3. Sampling method Use convenient sampling methods 2.2.4. Location and study time * Research location: The study was conducted at 4 Hanoi police schools. - Security Academy - T32 Police Academy - Police Political Academy - University of Fire Fighting and Prevention * Research period: The study was conducted over 3 years from December 2016 to December 2018. 2.2.5. Research facilities - Snellen vision table, eye examination microscope, automatic refractometer, AB ultrasound machine, Javal corneal refractometer, direct ophthalmoscope, lights: white light, stereoscopic vision kit: Fly test table and polarized sunglasses, Ishihara table of colors 38 tables, Pelli-Robson contrast vision board, Cyclogyl 1% polio. - Set of data collection slips. - Research records to record the necessary information. 2.2.6. Research content - Vision assessment: + Vision classification: - Good 20/20 – 20/50. - Average 20/50 – 20/200. - Poor Below 20/200 - Eye examination + Microscopic eye examination to identify the abnormalities of the eyeball. + Cross-eye examination, eye movement, detection of eyeball shock. + Investigate the maximum mydriasis, retinal condition assessment by direct ophthalmoscope. - Determination of refraction: + Use Refractometer + If the refractive error is identified, apply Cyclogyl 1% regulatory paralysis, and after 2 hours, measure by the refractometer to determine whether there is a refractive error, and adjust the glasses to achieve optimal vision. - Stereoscopic vision evaluation: Use the Fly test table to assess the stereoscopic vision level. 9 - Evaluation of color vision: Use Ishihara color vision board. - Evaluation of contrast vision Use the Pelli-Robson optometrist board. - Assessing perceptions of refractive errors: Use the data collection form. 2.2.7. Research variables - Gender characteristics. - Age group characteristics. - Characteristics of refractive errors. - Classification of vision: + Good + Average + Poor - Classification of stereoscopic vision: + Available + Absent Classification of color vision: + Normal + Color blind red-green color blindness, blue-yellow color blindness and total color blindness. - Classification of contrast vision: + Good + Average + Poor - Analysis of some factors related to visual function: + Some risk factors for myopia. + Some factors affecting stereoscopic vision. + Some factors affecting color blindness. + A number of factors affecting contrast vision. - Analyze the effectiveness of behavior change: + Proper knowledge about refractive errors. + Proper knowledge about the causes of refractive errors in daily life and study - Behaviors that affect refractive errors: lower head when studying, studying while lying in bed, looking closely at an object for more than 2 hours. - Change of behavior in 1 year of the researched student group. - Changes in vision within 1 year of the group of myopia students. - Myopia progression in 1 year of myopia student group. Assessing myopia progression: + Slow progression when myopia level increases: < -0,5 D annually 10 + Average progression when myopia level increases: -0,5 D → -1,0 D yearly. + Rapid progression when myopia level increases: -1,25 D → -1,75 D/yearly. + Rapid progression when myopia level increases: ≥ - 2,00 D/ year. - Changes in some biological indicators of the eyeball: eyeballs’ axis length, corneal curvature. Assessing the length of the eyeball axis: + Slowly progressing: ≤ 0,18 mm/year. + Averagely progressing: 0,19 - 0,36 mm/year. + Rapidly progressing > 0,36 mm/year 2.2.8. Data processing The collected data of the study was processed according to the medical statistical algorithms on the computer with the help of SPSS software version 2.2. Use T test when comparing quantitative variables and test 2 to compare qualitative variables, Fisher’s Exact test and Phi and Cramer test to verify the statistics are closely related. The difference is statistically significant when p value is ≤ 0.05. Assess the relationship between visual function and influencing factors by calculating the odds ratio (OR). Compare rates using χ2. CHAPTER 3 RESEARCH RESULTS 3.1. THE CHARACTERISTICS OF THE SUBJECTS OF THE STUDY 3.1.1. Gender characteristics Of the 400 study subjects, 352 males accounted for 88% and 48 females accounted for 12%. The number of male students is higher than the number of female students, the difference is statistically significant with (p <0.05). 3.1.2. Age characteristics The average age of the study subjects was 22.37 (the lowest was 20 years, the highest was 33 years). In which, the age group of 21 accounted for the highest proportion (28.5%), followed by the remaining 22 years (23.5%), scattered in other age groups. 3.2. RESULTS OF VISION FUNCTION 3.2.1. The situation of myopia in researched student group 3.2.1.1. The level of vision of researched student group Out of 400 students examined, 47 students showed signs of visual impairment, accounting for 11.75%, vision loss mainly ranged from 0.4 to 0.2 LogMar. 3.2.1.2. The situation of refractive defects after regulatory paralysis Before the regulatory paralysis, there were 47 students with visual impairment (11.75%). After regulatory paralysis, there were 15 students 11 without refractive errors. Among 32 students with refractive errors, all 32 cases were nearsighted, no cases of farsightedness and astigmatism. 3.2.1.3. Situation of refractive error The main cause of visual impairment in police school students is myopia refractive errors, accounting for 8%. Out of 400 students examined at 4 schools, 32 were found to be nearsighted, none of farsightedness and astigmatism. 3.2.1.4. Situation of myopia after Lasik surgery Of the 56 students who had Lasik surgery, there were 04 students who had myopia relapse, accounting for 7.1%, 52 students who had Lasik surgery without relapse had the proportion of 92.9%. 3.2.1.5. Level of myopia Out of 32 near-sighted students, most students with low-grade myopia accounted for 78.1% (myopia from -1.0D-3D), mediumsightedness (myopia from -3.0D to <-6.0D) accounts for 18.8%, myopic severity (myopia ≥ -6.0D) accounts for 3.1%. 3.2.1.6. Distribution of myopia students by the time of discovery The percentage of newly discovered myopia case at the examination accounted for the highest proportion (71.86%), followed by the rate of myopia with patients wearing glasses (15.64%), the rate of myopia after Lasik surgery ( 12.5%) of the 32 nearsighted students in the study group 3.2.2. Stereoscopic vision measurement results 3.2.2.1. Stereoscopic vision by gender The average stereoscopic vision is 30.3732.07 arc seconds. In which the average stereoscopic vision in men is 30.4633.04 arc seconds, the average stereoscopic vision in women is 29.6924.00 arc seconds. 3.2.2.2. Stereoscopic vision by age The lowest average stereoscopic vision at the age of 21 is 25.7913.78 arc seconds, the highest at the age of 24 is 35.9536.95 arc seconds. The average stereoscopic vision in the study group was 30.3732.07 arc seconds. There was no significant difference in the average stereoscopic vision in all the age group in the study group (p> 0.05). 3.2.2.3. Stereoscopic vision with refractive errors Table 3.13. Stereoscopic vision with refractive errors Stereoscopic vision Refractive errors Myopia (n=32) Normal (n=368) General LTTB+SD vision Min-max 32,38  28,6 30,19  32,38 30,37  32,07 16 – 160 16 – 400 16 - 400 12 Of the 400 students who have their stereoscopic vision measured The results show that the average stereoscopic vision in myopia students is 32.38 28.6 seconds arc, normal students are 30.1932.38 arc seconds, the average stereoscopic vision is 30.3732.07 seconds arc. 3.2.3. Color vision measurement results 3.2.3.1. Color vision of the subject of the study Table 3.14 Color vision of the subject of the study Color vision Normal Color blindness: Total Amount 388 12 400 Ratio % 97.0 3.0 100 Of the 400 students who were examined in color, 388 students with normal color vision accounted for 97% and 12 students with color blindness accounted for 3%. 3.2.3.2. Color vision of the subject of the study by gender Color blindness is mainly detected in men, there is no case of female color blindness. However, this difference is not statistically significant with (p> 0.05). 3.2.3.3. Characteristics and levels of color blindness Green blindness accounts for a higher proportion (58.3%) compared to red blindness (41.7%). Among the 12 cases of color blindness, light color blindness accounted for the highest rate of 50%, followed by moderate color blindness 33.33%, severe color blindness 16.67%, there was no case of complete color blindness. 3.2.4. Contrast vision measurement results 3.2.4.1. Contrast vision of the researched subjects The researched subjects had average contrast vision for both eyes, for the left eye (1,490.31 log), for the right eye (1,490.32 log) average contrast vision of 2 eyes (1,680.28 log) higher than 1 eye. 3.2.4.2. Contrast vision based on age and gender There was no significant difference in one-eye and both-eye contrast between the age groups and gender in the researched groups. The average contrast vision of one eye in all age groups is 1,490.32 logs, that of the two eyes is 1,680.28 logs. 3.3. FACTORS AFFECTING VISION FUNCTION 3.3.1. Some risk factors for nearsightedness in Police students 3.3.1.1. The relationship between myopia and gender The percentage of male students who are nearsighted is 3 times higher than that of female students. The difference was statistically significant with (p <0.05). There is a relationship between myopia and gender in the researched group 13 3.3.1.2. The relationship between myopia and age group The rate of myopia in the researched student group concentrates in the age group 21-22, scattered in other age groups. No correlation between myopia and age in researched student group (p> 0.05) 3.3.1.3. The relationship between myopia and family history Students in families with parents who are nearsighted are 2.38 times more likely to be nearsighted than students in families without myopia. This difference is statistically significant (p = 0.038 <0.05). 3.3.1.4. The relationship between nearsightedness and activity time close Near-sighted activities like reading, using computers, phones, watching TV and playing video games for more than 8 hours a day are closely related to myopia in the researched group with (p < 0.01). 3.3.1.5. The relationship between myopia and time spent outdoors Students who participate in outdoor activities for more than 2 hours a day, such as sports, and participate in extracurricular activities, are less likely to have myopia compared to students whose outdoor activities time is under 2 hours / day. The difference was statistically significant with (p <0.05). 3.3.2. Several factors affect stereoscopic vision 3.3.2.1. Relationship between stereoscopic vision and gender The average stereoscopic vision in men is 30.5833.28 arc seconds, in women is 29.0223.04 arc seconds. There was no significant difference in the level of stereoscopic vision between men and women in the researched group (p> 0.05). 3.3.2.2. Relationship between stereoscopic vision and refractive errors The average stereoscopic vision in the group of myopia student is 32.3828.6 seconds arc, the normal student group is 30.1932.4 seconds arc. There was no significant difference in stereoscopic vision between myopia and normal students. The difference is not statistically significant with (p> 0.05). 3.3.2.3. Relationship between stereoscopic vision and myopia level The average stereoscopic vision in a case of students with severe nearsightedness (40 second arc) is lower than the group of students with mild myopia (32.831.59 arc seconds) and average ones (29.3316.08 arc seconds) ). However, this difference is not statistically significant with (p > 0.05). 3.3.3. Several factors affect color blindness 3.3.3.1. Relationship between color blindness and family history There were 12 cases of color blindness among 400 students examined. In particular, the number of students who are color blind with a history of parents with color blindness is 4 students, accounting for 100%, higher than the rate of students who are color blind without a 14 parent history of color blindness, which are 8 students accounting for 2%. This difference is statistically significant with (p < 0.01). 3.3.3.2. The relationship between color blindness and gender The total number of male students is 352, with 12 students who detect color blindness accounting for 3.5%. While the total number of female students was 48, no cases of color blindness were detected. However, this difference is not statistically significant with (p> 0.05). 3.3.3.3. Relationship between color blindness and refractive error The group of students with normal color vision and without refractive errors accounts for a high proportion (97.3% and 93.7%). Meanwhile, the group of color blind students with myopia had a higher proportion (6.3%) than the group of color blind students without refractive errors (2.7%). However, this difference is not statistically significant with (p> 0.05). 3.3.4. Some factors affecting contrast vision 3.3.4.1. Relationship between contrast vision and gender The average contrast vision of each eye and both eyes in men is always higher than women. The difference was statistically significant (p <0.01). 3.3.4.2. Relationship between contrast vision and refractive error Table 3.40 Relationship between contrast vision and refractive error The average contrast vision in the group of students without refractive errors (1.690.27 log) is higher than the average contrast vision in the student group with myopia (1.590.27 log). This difference is statistically significant with (p <0.05). 3.4. THE EFFICIENCY OF CHANGE IN BEHAVIOR IN RELATION TO THE DEVELOPMENT OF MYOPIA 3.4.1. Change of student's awareness regarding nearsightedness Table 3.42. Students’ awareness about nearsightedness before and after intervention Passed Passed Passed Before After intervention intervention SL Ratio % Quantity Ratio % 158 39.5 299 74.8 142 35.5 293 73.3 147 36.8 289 72.3 < 0,001 < 0,001 < 0,001 Passed 154 < 0,001 Students’ awareness Definition Cause Negative effects Preventive methods myopia 38.5 288 72 p 15 After the intervention, the percentage of students who know about the concept, causes, harms and how to prevent myopia increases significantly. This difference is statistically significant with (p <0.001) 3.4.2. Changes in students’ behavior towards nearsightedness Table 3.43. Students’ behavior towards nearsightedness before and after the intervention before intervention After intervention Students’ behavior Towards nearsightedness Quantity Ratio % Quantity Ratio % Lowered neck Yes 112 28 89 22.3 Study while Yes 34 8.5 27 6.8 lying in bed Look at object closely for Yes 261 65.3 178 44.5 more than 2 hours p < 0,001 0.016 < 0,05 < 0,001 After the intervention, the rate of students who have lowered necks when studying decreases, the rate of students lying in bed when reading also decreases and the time for near-sighted activities such as using computers, phones, playing video games is also reduced. This difference is statistically significant with (p <0.001). 3.4.3. Myopic changes before and after the intervention The average level of myopia after intervention (1.41 ± 1.26D) is lower than the average level of myopia before intervention (1.88 ± 1.22D). The difference was statistically significant with (p <0.001). 3.4.4. Vision changes before and after the intervention There was a difference in average vision of myopia student group after intervention (0.24 ± 0.12), better than those before intervention (0.30 ± 0.13). This difference is statistically significant with (p <0.001). 3.3.5. The change in the length of the eyeball axis before and after the intervention There was no difference in the length of the eyeball axis before and after the intervention of the group of myopia students at the researched schools with (p> 0.05). 3.3.6. Corneal refraction before and after intervention The average corneal refraction after intervention (43.55 ± 0.26) was slightly lower than before the intervention (43.59 ± 0.25) but in general it was not significantly reduced. There was no statistically significant difference between corneal refraction before and after intervention (p> 0.05). 16 Chapter 4: DISCUSSION 4.1. CHARACTERISTICS OF SUBJECTS PARTICIPATING IN THE STUDY Our study was conducted on 400 subjects who are 3rd year students of 4 Hanoi police schools, the results showed that: The proportion of men accounts for 88%, and that of women accounts for 12%. The average age of the study subjects is 22.37; the lowest is 20 years old, the highest is 33 years old, the most common is 21 years old. The reason we selected the researched group in this age group is as follow: Firstly, we found that at this age, the growth and development of the human body has reached the highest level, the length of the eyeball axis is relatively stable so the rate of myopia at this age rarely face any fluctuations. It is worth noting that a number of students who had been admitted to the police schools have had surgery to treat refractive defects to comply with the specific commitment of the Public Security Department. But after a period of intense learning and training, there were changes in eyesight and refractive errors in the eyes. Secondly, we examine them to detect color disorders at this age for the purpose of giving advice to the subjects. Currently in Vietnam as well as in the world, there is no complete treatment for color blindness. Therefore, the awareness of color disorders is extremely important for police students, so that after graduation they will choose an appropriate job position for themselves. 4.2. RESULTS OF VISION FUNCTION 4.2.1. The status of myopia in researched student group 4.2.1.1. Actual nearsightedness after regulatory paralysis Out of 400 students examined, 47 students showed signs of vision loss and refractive errors, accounting for 11.75%. After applying the regulatory paralysis drop for the above 47 students, the results showed that 15 students without refractive errors and vision returned to normal after re-examination, 32 students are found with refractive errors. Among 32 students with refractive errors, all 32 cases were nearsighted, accounting for 8%, without presbyopia and astigmatism. The result also found that the rate of refractive errors decreased significantly after regulatory paralysis by 3.75%. 4.2.1.2. The status of myopia in the researched schools The study results show that the rate of myopia in the researched group is 8%, this result is similar to our previous research results in 2016 of 10.14%. In the study of author Nguyen Minh Tu et al (2014) on 1129 firstyear students of Hue University of Medicine and Pharmacy, the results showed that the rate of refractive errors accounted for 43.84%. 17 Compared with the results of the above authors, the results of our study have a lower rate of myopia. This can be explained that the admission work at the Public Security schools is relatively strict and requires the first-class eye health to be admitted to the industry. Therefore, this somewhat limits the rate of myopia students enrolled in the school. 4.2.1.3. The status of myopia by gender Results of the study show that the rate of myopia in male students is 3 times higher than female students. The difference was statistically significant with (p <0.01%). This can be explained by the fact that male students use their eyes when looking closer than female students to use computers to play games, phones and read stories ... Therefore, the eyes will have to regulate much more intensively when looking closely. 4.2.1.4. The status of newly-discovered myopia cases during examination The research results show that the rate of newly-discovered myopia cases during examination accounts for the highest proportion (71.86%), while the rate of myopia with glasses before is 15.64% and myopia rate after Lasik surgery is 12.5%. Research results for routine eye examinations are important for detecting students with reduced vision. 4.2.2. Stereoscopic vision measurement results The results of our study show that the average stereoscopic vision in the group of students without refractive errors is 30 arc seconds, and that in myopia student group is 32 arc seconds. Research by William J. Benjamin (2006) reported that the stereoscopic vision in normal humans was 40 arc seconds. Compared with the results of other authors, we found that the results of stereoscopic vision without refractive errors in our group was lower than in some studies of other authors. Author Sheery L. Fawcett (2014) studied 44 subjects without refractive errors, the average age of the study group was 35, giving stereoscopic vision of 40 arc seconds. The study of Hamed Momeni Moghadam et al. (2011) conducted on 174 students of Zahedan University of Medical Sciences aged 18 to 24, obtained stereoscopic vision of 45 arc seconds. The difference in results may be due to the use of kits for stereoscopic vision measurement. We use the improved Fly test kit. 4.2.3. Color vision measurement results 4.2.3.1. Color blindness detection rate We used the Ishihara test to test the color of all 400 subjects. As a result, 388 students with normal color vision accounted for 97%, 12 students with color blindness accounted for 3%. . Research by Tran Thi Thanh et al (2012) on subjects who are firstyear students at Hai Phong Medical University showed that the
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