ORGANIC CHEMISTRY
Dr Nam T. S. Phan
Faculty of Chemical Engineering
HCMC University of Technology
Office: room 211, B2 Building
Phone: 38647256 ext. 5681
Email: [email protected]
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Chapter 12:
CARBOXYLIC ACIDS
C=O
C=C
SP2 carbon
Y=OH
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NOMENCLATURE OF
CARBOXYLIC ACIDS
IUPAC names: hydrocarbon + “oic acid”
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4
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Some natural occurring acids & derivatives
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PREPARATIONS OF CARBOXYLIC
ACIDS
From Grignard reagents
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From nitriles
Have 1 more carbon as compared to the halide
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From primary alcohols
Can NOT be isolated
PCC: pyridinium chlorochromate
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From aldehydes
Aldehydes are generally easier to oxidize than
primary alcohols
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From alkylbenzenes
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REACTIONS OF CARBOXYLIC
ACIDS
Esterification
reactions
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IUPAC names: alkyl + carboxylate
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Intramolecular ester formation: Lactones
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IUPAC names: 2-oxacycloalkanone
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Reactions of esters
Ester hydrolysis
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Transesterification reactions
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Acyl chloride formation
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IUPAC names: replace “ic acid” with “yl halide” /
“carboxylic acid” with “carbonyl halide”
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Reactions of acyl chlorides
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